• Shopping Cart Shopping Cart
    0Shopping Cart
Aspire Medical Innovation
  • News
    • Blog
    • Newsletter
    • Events & Tradeshows
  • Products
    • Bone Marrow Aspiration
    • Bone Dowel Harvesting
    • Sub-Chondral Access
    • Platelet Plasma/PRP
    • Adipose Fat Grafting
    • Delivery Systems
    • Hematology
    • Other
      • Ergonomics
  • MARROW CELLUTION™
    • MARROW CELLUTION™
    • Product Details
    • Media & Presentations
    • References
    • Documents
    • FAQ
  • CERVOS KeyPRP
    • KeyPRP
    • Media & Presentations
    • Documents
    • FAQ
  • Resources
    • PRP Library
    • Online-Tools
    • Certificates & Documents
  • About
    • About us
    • What we do
    • Our Partners
  • Contact
  • Click to open the search input field Click to open the search input field Search
  • Menu Menu
You are here: Home1 / News2 / Marrow Cellution3 / MC Publication/Study4 / Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions...

Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year

01/08/2022/in Marrow Cellution, MC Publication/Study

Ignacio Dallo, Riccardo D’Ambrosi, Dawid Szwedowski, Ali Mobasheri, Alberto Gobbi.

Stem Cells and Development 2022 31:15-16, 488-497 | doi: 10.1089/scd.2021.0283

Abstract:

Bone marrow lesions (BMLs) are typical findings in magnetic resonance imaging present in different pathologies, such as spontaneous insufficiency fractures, osteonecrosis, transient BML syndromes, osteoarthritis, and trauma. The etiology and evolution of BMLs in multiple conditions remain unclear. There is still no gold standard protocol for the treatment of symptomatic BMLs in the knee. The biologic augmentation by Osteo Core Plasty™ is a new treatment modality showing promising results reducing pain with the aim to stop the progression of the disease. The purpose of this prospective study is to report the clinical outcomes and safety of Osteo Core Plasty for the treatment of symptomatic BMLs in the knee. Fifteen patients with symptomatic BMLs of the knee treated with the Osteo Core Plasty technique were included and followed prospectively for a minimum of 12 months. Each patient was evaluated before the surgery and respectively at 6 and 12 months using the Tegner Score, Marx Score, the International Knee Documentation Committee, the Knee Injury and Osteoarthritis Outcome Score divided in pain, activity daily living and quality of life subscale, and the Visual Analog Scale for pain. All clinical scores except Tegner and Marx score showed an overall statistically significant improvement through the entire follow-up (P < 0.05) and a significant improvement (P < 0.05) between each follow-up period (T0 vs. T1; T0 vs. T2; T1 vs. T2). No complications were reported. These preliminary results confirm that biological subchondral bone augmentation by Osteo Core Plasty technique is a safe and effective minimally invasive treatment option for symptomatic BMLs in the knee at 1-year follow-up. There is still a need for high-quality randomized controlled trials studies and systematic reviews in the future to enhance further treatment strategies in preventing or treating BMLs of the knee.

go to Journal

______________________________________________________

The Marrow Cellution™ System is designed to minimize and eliminate the restrictive limitations associated with “point of care” processing systems which employ inefficient traditional aspiration trocar technology and are regulated as drugs “Advanced Therapies Medicinal Products (ATMP)”.  Marrow Cellution™ is a minimally invasive bone/cell enriched autograft access and retrieval system, which does not require additional manipulation or processing, it never leaves the sterile field and provides rich autograft without associated morbidity.

Visit our Marrow Cellution product page

Share this entry:

  • share 
  • share 
  • share 
  • share 
  • share 
  • share 
  • email 
https://aspire-medical.eu/wp-content/uploads/2022/04/Dallo-feb22.jpg 348 918 admin https://aspire-medical.eu/wp-content/uploads/2025/02/AMI-Logo-web510x154.png admin2022-08-01 10:16:042023-01-23 16:18:48Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year
You might also like
The Impact of Volume on Related Cell Counts Using The MARROW CELLUTION™ Bone Marrow Aspiration System
Experts Achieve Consensus on a Majority of Statements Regarding Platelet-Rich Plasma Treatments for Treatment of Musculoskeletal Pathology
Osteo-Core-Plasty & HA-BMA Technique HA-BMA & Osteo-Core-Plasty™ Technique
Biologic Knee Arthroplasty in 360 Degrees for Early Osteoarthritis Treatment
Centrifuge RPM <> RCF Conversion
Sub-Chondral Bone Augmentation

Categories

Landing pages

Marrow Cellution™

CERVOS KeyPRP

JUVA PRP

Product Categories

Bone Marrow Aspiration

Bone Dowel Harvesting

Sub-Chondral Access

Platelet Plasma/PRP

Adipose Fat Grafting

Delivery Systems

Hematology

Other

Med. Specialities

Extremity

Intradiscal

Neuro Spine

Ortho Spine

Ortho / SportsMed

Pain Management

Plastic Surgery

Trauma

Company

About us

Providing Market Access

Our Partners

Events & Tradeshows

Newsletter

Blog

Contact

Resources

Online-Tools

PRP Library

Certificates

Intranet →

ASPIRE Medical Innovation  |  Einsteinstraße 167  |  81677 Munich  |  Germany

© Aspire Medical Innovation 2015-2025 │We ♥ our clients
  • Link to X
  • Link to LinkedIn
  • Link to Youtube
  • Link to Mail
  • Home
  • Terms
  • Privacy/Datenschutz
  • Disclaimer
Link to: The Use of Injectable Orthobiologics for Knee Osteoarthritis: a formal ESSKA consensus Link to: The Use of Injectable Orthobiologics for Knee Osteoarthritis: a formal ESSKA consensus The Use of Injectable Orthobiologics for Knee Osteoarthritis: a formal ESSKA...Link to: Short-Term Efficacy of Using a Novel Low-Volume Bone Marrow Aspiration Technique to Treat Knee Osteoarthritis: A Retrospective Cohort Study Link to: Short-Term Efficacy of Using a Novel Low-Volume Bone Marrow Aspiration Technique to Treat Knee Osteoarthritis: A Retrospective Cohort Study Short-Term Efficacy of Using a Novel Low-Volume Bone Marrow Aspiration Technique...
Scroll to top Scroll to top Scroll to top

This website uses cookies. These are small text files that are stored on your end device with the help of the browser. They do not cause any damage. Cookies are used to make our website user-friendly. By continuing to browse the site, you are agreeing to our use of cookies. Privacy Policy

ACCEPT ALLACCEPT ESSENTIAL ONLYPrivacy & Cookie Settings

Cookie and Privacy Settings



How we use cookies

Our website uses so-called cookies. These are small text files that are stored on your end device with the help of the browser. They do not cause any damage.

We use cookies to make our website user-friendly and to enrich your user experience. Some cookies may remain stored on your end device until you delete them. They enable us to recognise your browser on your next visit.

Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may limit your experience on our websites and the services we are able to offer.

Essential Website Cookies

These cookies are strictly necessary to provide you with services available through our website and to use some of its features.

Because these cookies are strictly necessary to deliver the website, you cannot refuse them without impacting how our site functions. You can block or delete them by changing your browser settings and force blocking all cookies on this website.

Analytical Cookies

These cookies collect information that is used either in aggregate form to help us understand how our website is being used or how effective our marketing campaigns are, or to help us customize our website and application for you in order to enhance your experience.

If you do not want that we track your visit on our site you can disable tracking in your browser here:

Functional Cookies

We also use different external services like Google Webfonts, Google Maps and external Video providers. Since these providers may collect personal data like your IP address we allow you to block them here. Please be aware that this might heavily reduce the functionality and appearance of our site. Changes will take effect once you reload the page.

Google Webfonts Settings:

Google Map Settings:

Vimeo and Youtube video embeds:

Product catalogue Settings:

Privacy Policy

You can read about our cookies and privacy settings in detail on our Privacy Policy Page.

Privacy-Policy
Accept allAccept settingsHide notification only
Open Message Bar Open Message Bar Open Message Bar

Add Aspire Medical to your Homescreen!

Add