Packaging update for Marrow Cellution

Transition to MDR and Reduction of Carbon Footprint


Ranfac Corp. and Aspire Medical Innovation GmbH continue to identify steps to reduce its carbon footprint, minimize inventory SKU, reduce waste and streamline its product portfolio.

As Marrow Cellution utilization continues to grow exponentially, we are taking serious steps to consolidate various versions of the Marrow Cellution kit configurations.  Effective January 1, 2022, we will be introducing a Marrow Cellution universal kit packaging configuration for the MC-RAN-11C and the MC-RAN-8C.

In order to reduce plastic packaging while maintaining regulatory compliance, we will be moving to a kit configuration that is single pouched.  This will permit us to have a single global SKU internationally recognized product offering.

The Marrow Cellution will continue to be packed in a tamper evident outer box.  The internal kit will be packed in one single pouch to be opened aseptically outside of the sterile field so that the internal plastic tray can be retrieved by sterile field operator.

A single step, centrifuge-free method to harvest bone marrow highly concentrated in mesenchymal stem cells: results of a pilot trial

Viganò M, Ragni E, Di Matteo B, Gambaro FM, Perucca Orfei C, Spinelli G, Colombini A, de Girolamo L, Kon E.

Viganò M, et al. Int Orthop. 2021 Nov 2. | doi: 10.1007/s00264-021-05243-7

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A review of bone marrow lesions in the arthritic knee and description of a technique for treatment

Alberto Gobbi, Ignacio Dallo, Rachel M. Frank, Hannah Bradsell, Ivan Saenz, and William Murrel

Gobbi A, et al. Journal of Cartilage & Joint Preservation; ePub: 18 Aug 2021. | doi: 10.1016/j.jcjp.2021.100021

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Injection of Bone Marrow Aspirate for Glenohumeral Joint Osteoarthritis: A Pilot Randomized Control Trial

Tim Dwyer, Graeme Hoit, Adrienne Lee, Elyse Watkins, Patrick Henry, Tim Leroux, Christian Veillette, John Theodoropoulos,  Darrell Ogilvie-Harris, and Jaskarndip Chahal

Dwyer T, et al. Arthroscopy, Sports Medicine, and Rehabilitation; ePub: 14 Aug 2021. | doi: 10.1016/j.asmr.2021.07.005

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Treating proximal tibial subchondral cystic lesion with Osteo-Core-Plasty

Osteo-Core-Plasty Case Report from Drs. Gobbi & Dallo from Milan/Italy

HA-BMA & Osteo-Core-Plasty™ Technique


In this video Dr. Alberto Gobbi and Dr. Ignacio Dallo present their new approach to treat Osteochondral Unit Pathology:

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Advancements in Joint Preservation: A Novel Alternative to Traditional Arthroplasty

CERVOS Master Class


Recent randomized controlled trials covering several hundred patients with approximately 15 year follow up have documented that biologic repair of subchondral lesions for patients with osteoarthritis and osteonecrosis is a viable alternative to total knee arthroplasty. Read more

Bone Marrow Aspirate Matrix: A Convenient Ally in Regenerative Medicine

José Fábio Lana, Lucas Furtado da Fonseca, Gabriel Azzini, Gabriel Santos, Marcelo Braga, Alvaro Motta Cardoso Junior, William D. Murrell, Alberto Gobbi, Joseph Purita and Marco Antonio Percope de Andrade

Lana JF, et al. International Journal of Molecular Sciences. 2021; 22(5):2762. | doi: 10.3390/ijms22052762

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Osteo-Core Plasty: A Minimally Invasive Approach for Subchondral Bone Marrow Lesions of the Knee

Dawid Szwedowski, Ignacio Dallo, Eleonora Irlandini, Alberto Gobbi.

Szwedowski D, et al.  Arthroscopy Techniques. 9;11 (2020) e1773-e1777  |  doi: 10.1016/j.eats.2020.07.023

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Positive early clinical outcomes of bone marrow aspirate concentrate for osteoarthritis using a novel fenestrated trocar

Nathan H Varady, Graham Cate, Ameen Barghi, Natalie Jobe, David Yakin, Ramon C Ylanan, Christopher A Arnold.

Varady NH, et al. Knee. 2020 Sep 23;27(5):1627-1634. | doi: 10.1016/j.knee.2020.08.018.

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