Bone Marrow Aspiration & Bone Harvesting Systems



Maximize Cell Yield & Percutaneous Bone Graft Harvesting

The Marrow Cellution™ System maximizes stem and progenitor cell recovery and minimizes excess blood collection.
Thus, it prevents the subsequent need for additional manipulation procedures such as centrifugation and/or chemical separation which usually require oversight by national regulatory authorities.


Reduces Excess Blood Collection

Closed-end Aspiration Design

Cannula via Sheath Technology

Lateral vs. Distal Collection


Never Leaves Sterile Field

Higher CFU-f Counts per mL

Autologous Bone Graft Collection

Additional Steps Not Required


Minimally Invasive

Low Volume—High Yield & Quality

Single Puncture—Multiple Aspirations

Regulatory Compliant

A breaktrough marrow aspiration system
offering high concentrations of stem cells
ready to use in an office setting
in less than 10 minutes

Marrow Cellution provides substantial savings in time, effort and expense.

It reduces patient trauma, morbidity and risk of infection.

Bone Marrow Aspiration

The regenerative qualities of bone marrow have been used for decades and are considered the gold standard for stem cell harvesting. However, after the first 1-2 mL of bone marrow aspirate from a traditional needle, the number of total nucleated cells (TNC) in the aspirate drops dramatically due to the lower viscosity of blood and the design of the needle, which operates most optimally for small biopsy volume. After aspirating the first 1-2 mL of bone marrow, peripheral blood will preferentially fill the vacated space, limiting the additional harvest of key stem and progenitor cells.

The Marrow Cellution™ Bone Marrow Aspiration System overcomes this issue. It allows the user to aspirate in a measured and controlled manner over a large geography inside the marrow space, while restricting peripheral blood infiltration.

Traditional Trokar Aspiration

Traditional Trocars collect additional excess peripheral blood, diminishing cellular yield; thereby requiring additional manipulation steps to achieve the cellular demand necessary for most clinical indications.

Marrow Cellution harvests high quality stem and progenitor cells from various levels within the marrow space, while limiting peripheral blood contamination.

Marrow Cellution™ harvests high quality stem and progenitor cells from various levels within the marrow space, while limiting peripheral blood infiltration. The system never leaves the sterile field and does not require further manipulation.

Functional design

Marrow Cellution™ Bone Marrow Aspirate System

High Quality Marrow Aspiration — Minimal Manipulation

The Marrow Cellution™ Bone Marrow Aspiration System is intended for use for aspiration of bone marrow or autologous blood. It allows the user to aspirate in a measured and controlled manner over a large geography inside the marrow space.

Marrow Cellution™ is available in both 11G and 13G and includes an introducer needle, blunt stylet, aspiration cannula and 10mL syringe. The technology is available in multiple lengths and is designed for use in the Iliac Crest, Pedicle, Calcaneus or Tibia.

What makes the difference?

Every Marrow Cellution™ System includes two important unique features that are not capable with a traditional needle:

  • A closed-tip aspiration cannula that only allows aspiration through the side holes of the cannula, blocking the channel created by the needle tip. This feature avoids excessive peripheral blood infiltration.
  • A mechanical means for measured and controlled retraction of the aspiration cannula to collect bone marrow aspirate from multiple geographies inside the medullary space with a single puncture.
Closed Tip & Threaded Handle

Bone Marrow Aspiration with Marrow Cellution™

Animation: Bone Marrow Aspiration with the Marrow Cellution™ System

Optimal Syringe Size & Plunger Aspiration Technique
to Maximize Cell Recovery

View the basic Marrow Cellution™
process steps overview

Scientific data: CFU-f counts

Marrow Cellution™ vs. Centrifuge Systems & Traditional Needle

Chart by Visualizer

(1) n=5; Scarpone MA, et al. Marrow Cellution Bone Marrow Aspiration System and Related Concentrations of Stem and Progenitor Cells. White Paper 2015.
(2) n=30; Scarpone MA, et al. Isolation of clinically relevant concentrations of bone marrow mesenchymal stem cells without centrifugation. J Transl Med (2019) 17:10.
(3) n=27; Harrell DB, Purita JR. Novel Technology to Increase Concentrations of Stem and Progenitor Cells from Marrow Aspiration. White Paper 2016.
(4) Hegde V, et al. A prospective comparison of three approved systems for autologous bone marrow concentration demonstrated non-equivalency in progenitor cell number and concentration. J Orthop Trauma. 2014 Oct;28(10):591-8.
(5) McLain R, et al. Aspiration of Osteoprogenitor Cells for Augmenting Spinal Fusion: Comparison of Progenitor Cell Concentrations From the Vertebral Body and Iliac Crest. J Bone Joint Surg Am. 2005 Dec; 87(12): 2655–2661.

Bone marrow aspiration & percutaneous cancellous bone harvesting

(MC-RAN-8 family)


High Quality Bone Marrow Aspirate and

Percutaneously Harvested Cancellous Bone Autograft

The high cellular composition of Marrow Cellution™ aspirate combined with percutaneously harvested bone cores delivers autograft without the associated morbidity.

Bone dowel harvesting with MC-RAN-8C

Autologous Bone Core Harvesting

MC-RAN-8C: Components (package also includes one 10ml syringe)

Marrow Cellution™ Bone Marrow Aspiration- & Autologous Bone Harvesting System


  • Gold standard graft material

    Delivers graft material with osteoconductive, osteoinductive & osteogenic properties.

  • Allows highly active combination graft

    Graft material may be combined with autologous, allogenic, xenogenic or synthetic bone chips hydrated with high cellular marrow aspirate.

  • Less morbidity at the donor site

    Reduces donor site morbidity associated with standard harvesting techniques.

In most countries, the ability to harvest bone graft allows the surgeon to be eligible for additional Diagnostic Related Group (DRG) compensation for autologous bone harvesting and transplantation.

Bone Dowel Harvesting with Marrow Cellution™ 8C

Animation: Marrow Cellution™ – Percutaneous Autograft Collection

Using the Marrow Cellution™ graft delivery syringe and the Bone Core Harvest device, the clinician can create a combination graft of a vascularized intact bone core in the center of the graft surrounded by allogeneic, autologous or synthetic bone chips hydrated with high cellular marrow aspirate.

Higher quality, less quantity, delivered appropriately minimizes host morbidity

Ease of use …

See the basic process steps for Marrow Aspiration
and Bone Core Harvesting


In-Office BMC done quickly and efficiently that is comfortable and convenient for both the patient and the provider. I love this trochar!

Hands down, the best method is the new Marrow Cellution needle. It’s a game changer. Far easier to use, only one insertion point through the PSIS (rather than multiple entry sites through the ilium), and a MUCH better stem cell yield than the traditional Jamshidi needle approach.

My patients outcomes have improved greatly and quicker since I started using the Marrow Cellution bone marrow needle.

Results have been better doing the aspiration from different depths with no centrifugation. I have not centrifuged bone marrow in a few years.

For the same patient and procedure, the measured number of progenitor cells per cc in the aspirate alone was comparable to the centrifugation concentrate protocol.

I am always suspicious that when we centrifuge bone marrow aspirate we might be throwing away significant aspects of the regenerative potential of biologic.

This is potentially a giant step in bone marrow processing. This needle will usher in a new age in bone marrow aspiration.

Don’t miss …

See our latest Marrow Cellution™ brochure

Marrow Cellution Brochure