Reduces Excess Blood Collection
Closed-end Aspiration Design
Cannula via Sheath Technology
Lateral vs. Distal Collection
The regenerative qualities of bone marrow have been used for decades and are considered the gold standard for stem cell harvesting. However, after the first 1-2 mL of bone marrow aspirate from a traditional needle, the number of total nucleated cells (TNC) in the aspirate drops dramatically due to the lower viscosity of blood and the design of the needle, which operates most optimally for small biopsy volume. After aspirating the first 1-2 mL of bone marrow, peripheral blood will preferentially fill the vacated space, limiting the additional harvest of key stem and progenitor cells.
The Marrow Cellution™ Bone Marrow Aspiration System overcomes this issue. It allows the user to aspirate in a measured and controlled manner over a large geography inside the marrow space, while restricting peripheral blood infiltration.
Traditional Trocars collect additional excess peripheral blood, diminishing cellular yield; thereby requiring additional manipulation steps to achieve the cellular demand necessary for most clinical indications.
Marrow Cellution™ harvests high quality stem and progenitor cells from various levels within the marrow space, while limiting peripheral blood infiltration. The system never leaves the sterile field and does not require further manipulation.
Marrow Cellution™ Bone Marrow Aspirate System
The Marrow Cellution™ Bone Marrow Aspiration System is intended for use for aspiration of bone marrow or autologous blood. It allows the user to aspirate in a measured and controlled manner over a large geography inside the marrow space.
Marrow Cellution™ is available in both 11G and 13G and includes an introducer needle, blunt stylet, aspiration cannula and 10mL syringe. The technology is available in multiple lengths and is designed for use in the Iliac Crest, Pedicle, Calcaneus or Tibia.
Every Marrow Cellution™ System includes two important unique features that are not capable with a traditional needle:
Animation: Bone Marrow Aspiration with the Marrow Cellution™ System
Optimal Syringe Size & Plunger Aspiration Technique
to Maximize Cell Recovery
View the basic Marrow Cellution™
process steps overview
(1) n=5; Scarpone MA, et al. Marrow Cellution Bone Marrow Aspiration System and Related Concentrations of Stem and Progenitor Cells. White Paper 2015.
(2) n=30; Scarpone MA, et al. Isolation of clinically relevant concentrations of bone marrow mesenchymal stem cells without centrifugation. J Transl Med (2019) 17:10.
(3) n=27; Harrell DB, Purita JR. Novel Technology to Increase Concentrations of Stem and Progenitor Cells from Marrow Aspiration. White Paper 2016.
(4) Hegde V, et al. A prospective comparison of three approved systems for autologous bone marrow concentration demonstrated non-equivalency in progenitor cell number and concentration. J Orthop Trauma. 2014 Oct;28(10):591-8.
(5) McLain R, et al. Aspiration of Osteoprogenitor Cells for Augmenting Spinal Fusion: Comparison of Progenitor Cell Concentrations From the Vertebral Body and Iliac Crest. J Bone Joint Surg Am. 2005 Dec; 87(12): 2655–2661.
The high cellular composition of Marrow Cellution™ aspirate combined with percutaneously harvested bone cores delivers autograft without the associated morbidity.
Autologous Bone Core Harvesting
Marrow Cellution™ Bone Marrow Aspiration- & Autologous Bone Harvesting System
Animation: Marrow Cellution™ – Percutaneous Autograft Collection
Using the Marrow Cellution™ graft delivery syringe and the Bone Core Harvest device, the clinician can create a combination graft of a vascularized intact bone core in the center of the graft surrounded by allogeneic, autologous or synthetic bone chips hydrated with high cellular marrow aspirate.
Higher quality, less quantity, delivered appropriately minimizes host morbidity
Ease of use …
See the basic process steps for Marrow Aspiration
and Bone Core Harvesting
See our latest Marrow Cellution™ brochure