Tag Archive for: PRP

Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year

Ignacio Dallo, Riccardo D’Ambrosi, Dawid Szwedowski, Ali Mobasheri, Alberto Gobbi.

Stem Cells and Development 2022 31:15-16488-497 | doi: 10.1089/scd.2021.0283

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The Use of Injectable Orthobiologics for Knee Osteoarthritis: a formal ESSKA consensus

Part 1: Blood-derived Products (PRP)

Chairpersons: Laura de Girolamo, Lior Laver

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CERVOS KeyPRP Presentation

A new video showing the latest CERVOS PRP Presentation: Read more

Autologous Biologic Treatment with Fat, Bone Marrow Aspirate and Platelet Rich Plasma Is an Effective Alternative to Total Knee Arthroplasty for Patients with Moderate Knee Arthrosis

Chatwick Prodromos and Susan Finkle.

Medicines (Basel). 2020 Jun 25;7(6):37 | doi: 10.3390/medicines7060037

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Review for good platelet-rich plasma procedure in cosmetic dermatology and surgery

Moon Hee Kim, Hyeon Seob Byeon.

Kim MH, Byeon HS.  J Cosmet Med 2019; 3(1): 1-13.  doi: 10.25056/JCM.2019.3.1.1

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Centrifuge RPM <> RCF Conversion

The Relative Centrifugal Force (RCF)  is the amount of acceleration to be applied to the sample in the centrifuge. It depends on the Rotation Speed and the Radius of the rotor, and is relative to the force of Earth’s gravity (g-Force).

Unfortunately, many protocols and instructions only list the RPMs as a parameter for correct process setup. This is OK as long as you use only one type of rotor/centrifuge, but as soon as you try to use your process disposable on a different rotor/centrifuge, the original RPM values might be wrong if the rotor diameter differs.

Therefore, you have to convert the Rotation Speed (RPM) into Relative Centrifugation Force (RCF) and vice versa. For this purpose you will need the Rotor Radius of your centrifuge. The radius is measured from the axis of rotation to the inner bottom of the swing-out cup.

Once you have the value for the Rotor Radius “r” you can calculate RCF and/or RPM with the following formulas:

Here is a tool to calculate RCF and RPM – you just need to fill in your numbers and hit Return or TAB key:
(rotor radius fields below are pre-set with the BOOST 2+ Flex (Drucker Diagnostics) rotor radius value of 139mm as mentioned in the instructions)

CFU-f, Endothelial Cells & CD34+ Cells

Understanding the Relationship

Platelet Rich Plasma vs. Marrow Cell Composition

Growth Factor Strategy vs. Cell Driven Therapy