Tag Archive for: Bone Marrow Aspirate

A single step, centrifuge-free method to harvest bone marrow highly concentrated in mesenchymal stem cells: results of a pilot trial

Viganò M, Ragni E, Di Matteo B, Gambaro FM, Perucca Orfei C, Spinelli G, Colombini A, de Girolamo L, Kon E.

Viganò M, et al. Int Orthop. 2021 Nov 2. | doi: 10.1007/s00264-021-05243-7

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Positive early clinical outcomes of bone marrow aspirate concentrate for osteoarthritis using a novel fenestrated trocar

Nathan H Varady, Graham Cate, Ameen Barghi, Natalie Jobe, David Yakin, Ramon C Ylanan, Christopher A Arnold.

Knee. 2020 Sep 23;27(5):1627-1634 | doi: 10.1016/j.knee.2020.08.018.

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Autologous Biologic Treatment with Fat, Bone Marrow Aspirate and Platelet Rich Plasma Is an Effective Alternative to Total Knee Arthroplasty for Patients with Moderate Knee Arthrosis

Chatwick Prodromos and Susan Finkle.

Prodromos C, et al. Medicines (Basel). 2020 Jun 25;7(6):37 | doi: 10.3390/medicines7060037

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Comparison of Two Methods to Harvest Vertebral Body Marrow Aspirate: Novel Lateral Aspiration Device Compared to Standard Cannula Needle

Sabatino Bianco, Wade Aumiller.

Pilot Study | White Paper

This pilot study was designed with the objective of reporting the cellular content of the vertebral body by comparing the average number of connective tissue progenitor cells (CFU-f /mL) using a novel aspiration technology – Marrow Cellution (MC) – that employs small draws from a single puncture that promote only lateral flow from multiple sites (SSLM Method), and by using traditional aspiration needle (BMAC) as a control.

A secondary purpose of the study was to retrospectively compare the two different sample aspiration protocols tested in this study to previous studies where the aspiration was taken from the iliac crest or vertebral body.

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The Marrow Cellution™ System is designed to minimize and eliminate the restrictive limitations associated with “point of care” processing systems which employ inefficient traditional aspiration trocar technology and are regulated as drugs “Advanced Therapies Medicinal Products (ATMP)”.  Marrow Cellution™ is a minimally invasive bone/cell enriched autograft access and retrieval system, which does not require additional manipulation or processing, it never leaves the sterile field and provides rich autograft without associated morbidity.

Visit our Marrow Cellution product page

Osteo-Core-Plasty™ with Marrow Cellution™


Dr. Alberto Gobbi & Team from O.A.S.I. Bioresearch in Milan/Italy demonstrate an Osteo-Core-Plasty™ treatment on a patient with suchondral bone cyst in the knee.

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The Impact of Volume on Related Cell Counts Using The MARROW CELLUTION™ Bone Marrow Aspiration System

Michael A. Scarpone, Daniel Kuebler.

Pilot Study | White Paper

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Isolation of clinically relevant concentrations of bone marrow mesenchymal stem cells without centrifugation

Michael Scarpone, Daniel Kuebler, Andrew Chambers, Carlo Maria De Filippo, Mariangela Amatuzio, Thomas E. Ichim, Amit N. Patel, Eugenio Caradonna.

Scarpone et al. J Transl Med (2019) 17:10 | https://doi.org/10.1186/s12967-018-1750-x

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Marrow Cellution™ Bone Marrow Aspiration in an Office Setting


In this video, Dr. Kelly Scollon-Grieve from Premier Orthopaedics demonstrates how easy the Marrow Cellution system can be applied to aspirate bone marrow in an office setting.

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Autograft Bone Harvested from the Iliac Crest use in Challenging Fusion

Allister Williams, MD

Case Report

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Comparative Analysis of Marrow Cellution™ and Emcyte® BMC System

Michael A Scarpone, Daniel Kuebler

Comparative Analysis | White Paper

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