What the Experts Require:
- Platelet Rich Plasma must contain a higher concentration of platelets than baseline, however an increase in platelets is a very broad description of PRP and does not accurately describe the variability among different types of PRP.
- There are several parameters that need to be taken into account when considering PRP, including: platelet concentration above baseline, whether or not leucocytes are included, whether or not the PRP has been anticoagulated and whether it requires exogenous activation.
- Platelet count is the first variable to consider. Absolute platelet count varies depending on the platelet concentration in the subjects’ peripheral blood. PRP devices can be usually divided into lower (2,5 – 3 times baseline concentration) and higher (5 – 9 times baseline concentration) systems.
- It would seem intuitive that a higher platelet count would yield more growth factors and better clinical results, however, this has not yet been fully determined.
The International Cellular Medicine Society (ICMS) Platelet Rich Plasma (PRP) Guidelines 2011